The 15th-century palazzo belonging to Venice’s prominent Sagredo family lay abandoned for 25 years before work began on transforming it into the new and exclusive hotel, Ca’ Sagredo. It took seven years to renovate the frescoes, plaster work and wall-size canvases that the Sagredos collected and commissioned. The result is museum-like — incorporating 17th and 18th century paintings by Tiepolo, Ricci and Longhi — yet intimate, there are just 24 suites and 18 guest rooms. Even the standard rooms are large by Venetian standards. The palazzo’s original library – now a guestroom – is a national monument. The location of Ca’ Sagredo couldn’t be better – directly on the Grand Canal just steps from the Rialto Bridge and St. Mark’s Square. The hotel’s formal restaurant, serving Mediterranean fare, is right on the water and the bar has become a favorite of locals. Rates start at 385 euros per night.